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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAMTS20
All Species:
10.61
Human Site:
Y427
Identified Species:
21.21
UniProt:
P59510
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P59510
NP_079279.3
1910
214721
Y427
K
E
M
K
V
T
K
Y
H
V
M
A
P
A
L
Chimpanzee
Pan troglodytes
XP_528704
1935
216502
Q459
E
E
G
V
K
S
P
Q
H
V
M
A
P
T
L
Rhesus Macaque
Macaca mulatta
NP_001104009
1911
214939
Y428
R
E
M
N
V
T
Q
Y
H
V
M
A
P
V
L
Dog
Lupus familis
XP_852138
2091
233309
Y431
E
T
G
S
K
H
Q
Y
H
V
M
A
P
T
L
Cat
Felis silvestris
Mouse
Mus musculus
P59511
1906
212023
Y424
E
A
G
I
K
H
Q
Y
H
V
M
A
P
T
L
Rat
Rattus norvegicus
Q9WUQ1
967
105687
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505519
1995
223408
R436
E
G
V
H
K
G
C
R
T
Q
H
M
P
L
A
Chicken
Gallus gallus
XP_416037
1725
194026
H281
A
G
I
K
H
Q
Y
H
V
M
A
P
T
L
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002663807
2516
282446
Q416
E
D
G
V
K
N
Q
Q
H
V
M
A
P
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395557
1763
199932
A319
R
T
K
G
E
G
I
A
A
A
D
M
L
N
K
Nematode Worm
Caenorhab. elegans
Q19791
2150
242563
P456
N
N
F
H
I
M
A
P
T
L
E
Y
N
T
H
Sea Urchin
Strong. purpuratus
XP_791211
1693
190452
S248
C
D
P
L
R
S
C
S
I
V
E
D
N
G
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.3
94.1
69.1
N.A.
70.3
23.5
N.A.
57.2
57.1
N.A.
32.6
N.A.
N.A.
32
31.5
38.1
Protein Similarity:
100
67.6
96.9
78.3
N.A.
83.4
31.2
N.A.
70.7
71.7
N.A.
46.6
N.A.
N.A.
46.9
47
53.5
P-Site Identity:
100
46.6
73.3
46.6
N.A.
46.6
0
N.A.
6.6
6.6
N.A.
40
N.A.
N.A.
0
0
13.3
P-Site Similarity:
100
60
86.6
60
N.A.
60
0
N.A.
20
26.6
N.A.
60
N.A.
N.A.
6.6
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
0
0
0
9
9
9
9
9
50
0
9
9
% A
% Cys:
9
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% C
% Asp:
0
17
0
0
0
0
0
0
0
0
9
9
0
0
0
% D
% Glu:
42
25
0
0
9
0
0
0
0
0
17
0
0
0
0
% E
% Phe:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
17
34
9
0
17
0
0
0
0
0
0
0
9
0
% G
% His:
0
0
0
17
9
17
0
9
50
0
9
0
0
0
9
% H
% Ile:
0
0
9
9
9
0
9
0
9
0
0
0
0
0
0
% I
% Lys:
9
0
9
17
42
0
9
0
0
0
0
0
0
0
9
% K
% Leu:
0
0
0
9
0
0
0
0
0
9
0
0
9
17
59
% L
% Met:
0
0
17
0
0
9
0
0
0
9
50
17
0
0
0
% M
% Asn:
9
9
0
9
0
9
0
0
0
0
0
0
17
9
9
% N
% Pro:
0
0
9
0
0
0
9
9
0
0
0
9
59
0
0
% P
% Gln:
0
0
0
0
0
9
34
17
0
9
0
0
0
0
0
% Q
% Arg:
17
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
9
0
17
0
9
0
0
0
0
0
0
0
% S
% Thr:
0
17
0
0
0
17
0
0
17
0
0
0
9
42
0
% T
% Val:
0
0
9
17
17
0
0
0
9
59
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
34
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _